Kei te whai ko te CF CF kahore e whai ana koe ki te Fibrosis
Ko te fibrosis Cystic ko te mate urutomo e mate ana i te mate pukupuku me te mate, kaore i te pai te whakatipu i te raruraru me te paheke o te mate me te hinu, i nga papaa mai i te mahinga ngako i roto i te ngutu me te papanga.
Me tirotiro i te tauira tuku iho o te cystic fibrosis, tae atu ki nga waitohu tatauranga o te tamaiti kei te whakawhanake i te CF ki te mea ko nga matua e rua nga kaihoko CF.
Te Fibrosis Hiko: Te Maatau Mate Aukati
Ko ia tangata he 23 pai o nga chromosomes i roto i ia waea. Ko etahi o nga 23 e rua, kotahi te tokorua ko te chromosomes sex (te X chromosome me te Y chromosome) me nga atu 22 e rua o te chromosomes e kiia ana he autosomes.
Kei roto i ia hoa rua nga ira kotahi, engari kaore ano i te waehere ira ira. Hei tauira, ko nga chromosomes i roto i te tokorua e whakatau ana i te tae makawe ka whai i te ira tae, engari he parauri tetahi, me tetahi atu huruhuru.
Ko te fibrosis hauora ka puta mai i te whakawhitinga o te kaitautoko transmymbrane transmymbrane (CFTR) cystic fibrosis. Mena he potae CF koe, ko te tikanga o tetahi o ou ira CFTR he mea noa, me etahi atu he whakawhitinga e mohio ana ki te hanga i te fibrosis cystic.
Ka puta anake te fibrosis i te wa e rua nga kape o te ira CFTR he whakawhitinga-koinei te take e kiia ana te mate o te cystic fibrosis he mate turoro matekore, kaore i te mate o te mate autosomal (e kotahi anake te kape o te ira whakaheke e hiahiatia mo te whakawhanaketanga mate) .
Ko te kaitohu ko te mea ko koe, ko to hoa hoki nga kaihoko o te CF, ka taea e koe te tuku CF ki to tamaiti. Ko tenei no te mea ka whakawhiwhia to tamaiti ki tetahi o nga komihana o ia tokorua, me tetahi o to hoa. Mena ka whakawhiwhia e te tamaiti nga kape e rua o te kainoro kei roto i te ira a te CFTR, ka ruarua nga kape me te whanau mai ki te cystic fibrosis.
Mena ka whakawhiwhia mai e to tamaiti he irakino rereke mai i tetahi o koutou, he mea noa mai i tetahi atu, ka waiho hei kaitaha CF, engari kaore i te cystic fibrosis. Mena ka tohatohahia e to tamaiti te chromosome noa mai ia koe, ka rua ona kaari, kaore ia e mau ana, kaore hoki he CF.
Fibrosis Cystic: Taearanga Raraunga
Anei tetahi atu huarahi hei titiro i te tikanga o te kawe i te CF.
Ko nga mahi ka taea e nga kaiwhakahaere e rua o te CF te tuku ki a raatau tamariki:
- Normal CFTR mai i te mom + mutation mai i papa = te kawe
- Normal CFTR mai i te papa + whakawhitinga mai i te mom = kawe
- Normal CFTR mai i mama + CFTR noa mai i papa = e kore e kawe ana, kaore he CF
- Kua mutu te CFTR mai i te mama + ka whakawhiti i te CFTR mai i te papa = te hukaroki
Mena he kaihokohoko koe me to hoa, he 25 ōrau te whai wāhitanga o tō tamaiti ki te CF, he 50 ōrau te whai wāhi ki te kawe, me te 25 ōrau kaore e whai mana, e kore hoki e whai CF.
Mena kaore to hoa i te kawe i te CF, kaore e taea e to tamaiti te whai CF ki te mea ka taea e ia anake te tuku i nga kaute o te CFTR i to hoa. Engari, ki te riro i to tamaiti to whakawhitinga i te ira CFTR mai ia koe, ka 25 pea te waahanga o ia hei kawe. I tenei take, ka taea e to tamaiti te tuku i te tohu CF ki a raatau tamariki.
He aha te tikanga ki te waiho hei kaitiaki hauora
Mena he potae koe ki te CF, kaore koe i te tohu o te fibrosis cystic me te kore e whakaaro ki te whakawhanake i te mate. I tua atu, ko te kawe i te CF kaore e whakaroa i to waahi, ka whakawhitia ranei koe i tetahi huarahi (kaore i te whakamahere mahere).
Ina timata koe ki te whakaaro ki te whai tamariki , me rapu koe me to hoa ki te tohutohu tawhito hei whakatau i to paanotanga o te rere o te CF ki o tamariki tamariki ake nei. I tua atu, ka taea e koe te kite mehemea ko koe, ko to hoa hoki, he kaihoko CF i te tukunga i te whakamatau toto kia tirohia ai te ira CF.
He Kupu Mai i
Ko te mahinga whakamutunga ki te mohio, ko te mea i mua i nga kaupapa whakamatautau tamariki, ko te nuinga o te iwi i kite i te CF ka puta he tohu.
Na, mehemea kei te whakamatau te tamaiti i te whakamatau a te CF, ka whakamamaehia e ia he whakamatautau haumanu hei whakamutu i te taatai o te CF.
Ma te wera o te wera, ka tohua te tote o te wera o te pene. Ko nga tangata me te CF he tino teitei o te tote i roto i to ratou wera no te mea he ngoikore te wera o te wera.
Ma te whakamatautau o mua, ka taea te mahi i raro i tetahi kapa hauora CF hou i te wa poto. He maha nga kaitohutohu a tenei kapa (me te tumuaki pukupuku me te tohungatanga ki te CF), nga kaitautoko, he kaihautumahi, he kaitautoko hauora, he kaiwhakahaere hauora, he tohunga hinengaro, he kaimahi mahi hapori.
> Mahinga:
> Torpy JM, Lynm C, Glass RM. Te fibrosis. Tuhinga o te Patient JAMA. JAMA . 2009; 302 (10): 1130.
> Te Whare Wānanga o Virginia Health System. (2016). Fibrosis Cystic.